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Hydrogels versus Scaffolds: When to Choose What?

by Ossiform | August 24, 2023 | Scientific Blog Posts​

In modern research, a dichotomy of somewhat opposing methods is emerging; porous, structural scaffolds versus elastic, synthetic hydrogels. 

Both methods enable the creation of three-dimensional microphysiological systems (MPS) and thus carry the potential to more accurately mimic in vivo environments compared to 2D cultures. Each method presents their respective scientific advantages and limitations in recapitulating the properties of native tissues and is thus suitable for mimicking different types of tissues or in vivo environments. In consequence, to bridge this dichotomy, a distinction between when each method is more appropriate is necessary

How do bones function and what are they made of?​

by Ossiform | June 27, 2022 | Scientific Blog Posts​

The human body is composed of multiple specialized tissue types, each with unique properties which are tailored to support the different functions throughout the body. ​

One such tissue is our bones, which most of us would characterize as rigid, calcified structures that form the skeleton. Besides providing structure and stability to our bodies, together with our muscles and tendons, the skeleton also functions as a stem cell niche and a reservoir for inorganic ions like calcium and phosphate.​​​

The performance of 3D printed resorbable implants in the mandible of pigs​

by Ossiform | May 12, 2022 | Scientific Blog Posts​

3D printed patient specific implants derived from CAD/CAM-based technologies are presented as an alternative to preformed bone graft substitutes. Yet, today, clinicians must still choose between patient specificity or implant properties that are favorable for bone remodeling.

In this pilot study, the 3D printed P3D Bone has been directly compared to a commercially available off-the-shelf β-tricalcium phosphate implant in relation to defects in the mandible ramus of pigs. 

What 3D printing is all about

​by Ossiform | Jun 18, 2021 | BL​OG​​

3D printing may sound like something from a galaxy far, far away, but the technology has been around for quite some time. Throughout the years, scientists from all over the world have printed everything; from small food items to large scale houses, and in the medical industry, 3D printing is playing a key role in bettering both treatment, outcome, and overall patient satisfaction. 3D printing is providing a range of new possibilities for cost efficient production where less resources actually give you better results.

One of the many advantages of 3D printing is that you can test your ideas quickly – and if they don’t work, you can easily change them”, explains Philip Firouzian.​​

What are organoids and why are they important?​

by Ossiform ​| May 18, 2021 | Scientific Blog Posts

Organoids cover a wide range of three-dimensional multicellular in vitro human tissue constructs that are used to mimic its corresponding in vivo organ in research.

The word ‘organoid’ is relatively new and most commonly describes constructs derived from stem cells – either pluripotent or adult stem cells – from various organs. Still, stem cell-derived organoids are not the only type of organoid. In fact, there are a wide variety of organoids that are created through different types of cell culture systems. These include 3D bioprinted scaffolds, organ-on-chip, and microfluidics-based 3D cell culture models.​

Biofilm, a brief introduction​

​by Ossiform | Apr 16, 2021 | Scientific Blog Posts​

Biofilms are clusters of one or more living microorganisms, or microbes, such as bacteria, fungi, and viruses that are attached to a surface and embedded in a self-produced matrix designed for the survival of organisms.

And why should we pay attention to biofilms?​

How miniature tumors can be grown on P3D Scaffolds for cancer research​

​by Ossiform | Oct 21, 2020 | Scientific Blog Posts​

In the study of cancer, tumoroids (tumor-like organoids) represent a promising tool for cost-effective research and screening of anticancer therapies.​

How 3D cell culturing is revolutionizing the fields of disease modeling and regenerative medicine

​by Ossiform | Jul 19, 2020 | Scientific Blog Posts

The development of lifelike 3D bone environments represents a good example of how 3D printing technology is revolutionizing the future of medicine, yielding advances in biotechnology and drug development. Especially, with the capacity to overcome the shortcomings and drawbacks of conventional 2D cellular models and animal models, 3D cell cultures show huge potential in regenerative medicine and disease modeling.​​

Optimizing P3D Scaffolds based bone tumor models ― for cancer research on metastases to bone

​by Ossiform | Feb 12, 2021 | BL​OG​

Ossiform is happy to welcome our new research intern, Rie Andersen Lassen, who will be engaging in a new cancer model research project to optimize P3D Scaffolds-based tumor models for research on metastases to bone. That is, the spread of cancer cells from cancerous tumors to bone.​​

​​Want to stay up to date with the latest biotech news from our scientists?​

That's why, We Print Bone

Our mission is to provide 3D printed natural bone implants to reduce complications, improve functional & aesthetics outcomes, and obtain faster recovery

Natural bone porosity, optimized for bone regeneration

The unique structure of the P3D Bone is designed to facilitate the natural forming of new bone.

Remodels into real living bone

The natural material and structure ensure effective remodeling of the implant into new vascularized bone.

Patient specific - designed with the patient's uniqueness in mind

The P3D Bone is 3D printed to enable a full restoration of the functionality and appearance of bones. ​

Resorbable material with structural support

P3D Bone eliminates the need to harvest bone as well as the need for permanent and ill-fitting implants.

P3D Bone Void Filler is expected to launch in 2023

Our first 3D printed, resorbable P3D Bone with modifiable dimensions and a lifelike bone architecture.

P3D Bone Patient Specific Implant is expected to launch in 2024

Our patient specific and resorbable P3D Bone based on the patient's own CT/MRI scan data. ​

We Print Bone​™

Contact us here

Contact us for questions, general inquiries, or to request a quote.
We strive to provide you with highest quality service and expertise in medical 3D printing.

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Give us a call or send us an email: info@ossiform.com

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Ossiform ApS - We Print Bone™

​Oslogade 1, 5000 Odense C​, Denmark

CVR. 38838512

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