Scientific Blog Posts​

The performance of 3D printed resorbable implants in the mandible of pigs​

3D printed patient specific implants derived from CAD/CAM-based technologies are presented as an alternative to preformed bone graft substitutes. Yet, today, clinicians must still choose between patient specificity or implant properties that are favorable for bone remodeling.

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In this pilot study, the 3D printed P3D Bone has been directly compared to a commercially available off-the-shelf β-tricalcium phosphate implant in relation to defects in the mandible ramus of pigs. 

What are organoids and why are they important?​

Organoids cover a wide range of three-dimensional multicellular in vitro human tissue constructs that are used to mimic its corresponding in vivo organ in research.

The word ‘organoid’ is relatively new and most commonly describes constructs derived from stem cells – either pluripotent or adult stem cells – from various organs. Still, stem cell-derived organoids are not the only type of organoid. In fact, there are a wide variety of organoids that are created through different types of cell culture systems. These include 3D bioprinted scaffolds, organ-on-chip, and microfluidics-based 3D cell culture models.​

How 3D cell culturing is revolutionizing the fields of disease modeling and regenerative medicine

The development of lifelike 3D bone environments represents a good example of how 3D printing technology is revolutionizing the future of medicine, yielding advances in biotechnology and drug development. Especially, with the capacity to overcome the shortcomings and drawbacks of conventional 2D cellular models and animal models, 3D cell cultures show huge potential in regenerative medicine and disease modeling.​​