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P3D Bone - Patient Specific and Bioresorbable

Available soon

A Patient Specific and Resorbable Bone Graft Substitute

Ossiform is developing P3D Bone PSI, a Patient Specific Implant that remodels into real living bone. Made from 3D printed ß-tricalcium phosphate, the personalized implant delivers a resorbable material with a unique bone-like porosity. The result is a more natural implant in terms of both material, shape, and structure that enables a full restoration of the functionality and appearance of the patient's bones.

P3D Bone demonstrates osteoconduction with a rapid formation of new vascularized bone, osseointegration with native bone, and a simultaneous and balanced bioresorption (1).

The P3D Bone PSI requires no manual adjustment in the operating room and eliminates the need to harvest bone as well as the need for permanent and ill-fitting implants. With P3D Bone, surgeons will be able to provide an implant that precisely matches patient needs, and thereby improve patient outcomes, increase procedural efficiency, and minimize the risk of complications.​

Tricalcium Phosphate: The Optimal Synthetic Choice

Beta tricalcium phosphate (β-TCP) is the gold standard within synthetic bone graft materials (2). It is bioresorbable and biocompatible and has been widely used clinically for filling and reconstructing bony defects in orthopedic surgery and dentistry.

β-TCP is the major mineral of the intercellular composite of human bones; this is why we want to rebuild them using β-TCP as this mineral contains only phosphate and calcium.

The material has the potential to optimize and surpass the natural osteoconductive and osteoinductive qualities of autogenous grafts, thereby reducing complications such as infection, bleeding, and rejection (3).

Intended Use Case of P3D Bone PSI

Step 1​


The hospital or clinic performs a CT or MRI scan of the patient which is sent to Ossiform.

Step 2

3D Modeling

Based on the scan, Ossiform 3D models the patient specific implant using a software tool.

Step 3

Implant Design

The surgeon accepts an implant design, and this is sent to a conveniently located production hub.

Step 4

Ossiform Production Hub

The Ossiform production hub prints, sterilizes and freights the implant to the hospital or clinic.

Step 5


The hospital or clinic receives the implant from the nearby production hub and performs the surgery.

Effective Bone Reconstruction and 3D Bone Regeneration

P3D Bone is 3D printed with large interconnected and multidirectional macropores and canals to enhance cell attachment, growth, and migration and enable vascularization throughout the entire implant. This mimics the cancellous structure observed in human bones and induces the bone regeneration process.

The porous structure, with physiologically relevant macropores and micropores, enables a strong ingrowth of new native bone. Meanwhile, the implant’s natural chemical composition provides ideal conditions for a simultaneous bioresorption. This process ensures an effective remodeling of the implant into new vascularized bone (4).

(1) ​Jensen, M. B., Slots, C., Ditzel, N., Albrektsen, O., Borg, S., Thygesen, T., … & Andersen, M. Ø. (2018). Composites of fatty acids and ceramic powders are versatile biomaterials for personalized implants and controlled release of pharmaceuticals. Bioprinting, 10, e00027.

(2) ​Fernandez de Grado G, Keller L, Idoux-Gillet Y, Wagner Q, Musset AM, Benkirane-Jessel N, et al. Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management. J Tissue Eng. 2018;9:2041731418776819.​

​(3) ​St, T. J., Vaccaro, A. R., Sah, A. P., Schaefer, M., Berta, S. C., Albert, T., & Hilibrand, A. (2003). Physical and monetary costs associated with autogenous bone graft harvesting. American journal of orthopedics (Belle Mead, NJ), 32(1), 18-23.

(4) ​Thygesen, T., et al. Comparison of off-the-shelf β-tricalcium phosphate implants with novel resorbable 3D printed implants in mandible ramus of pigs. Bone (2022): 116370.

Our mission is your benefits

Our mission is to provide 3D printed natural bone implants to reduce complication, improve functional & aesthetics outcomes, and obtain faster recovery

Natural bone porosity, optimized for bone regeneration

The unique structure of the P3D Bone is designed to facilitate the natural forming of new bone.

Remodels into real living bone

The natural material and structure ensure effective remodeling of the implant into new vascularized bone.

Patient specific - designed with the patient's uniqueness in mind

The P3D Bone is 3D printed to enable a full restoration of the functionality and appearance of bones. ​

Resorbable material with structural support

P3D Bone eliminates the need to harvest bone as well as the need for permanent and ill-fitting implants.

P3D Bone Void Filler is expected to launch in 2023

Our first 3D printed, resorbable P3D Bone with modifiable dimensions and a lifelike bone architecture.

P3D Bone Patient Specific Implant is expected to launch in 2024

Our patient specific and resorbable P3D Bone based on the patient's own CT/MRI scan data. ​

We Print Bone​™

Contact us here

Contact us for questions, general inquiries, or to request a quote.
We strive to provide you with highest quality service and expertise in medical 3D printing.

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Do you have questions?

Give us a call or write to us by email: info@ossiform.com

We will get back to you as soon as possible.​

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Ossiform ApS - We Print Bone™

​Oslogade 1, 5000 Odense C​, Denmark

CVR. 38838512

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