Ossiform® has successfully provided researchers at the University of Oxford and the University of Southern Denmark with P3D Scaffolds. The goal is to help simulate a bone-relevant in vivo environment.

About the research team from the University of Oxford

​Currently, the prevention of prostate cancer bone metastasis is halted by palliative treatments and limited preclinical secondary bone cancer models. Consequently, no curative treatment exists for this cancer stage. However, researchers at the University of Oxford, led by Jia-Ling Ruan, aspire to advance appropriate therapies. They are integrating Ossiform’s P3D Scaffolds in their 3D tumor/organoid cultures. The aim is to develop an effective in vitro bone metastasis model. Utilizing FLASH radiotherapy, the researchers can buoyantly study the effects of radiation responses of normal bone tissue/tumor and the abscopal effects of secondary bone metastasis, respectively.

About the research team from the University of Southern Denmark

A plethora of publications have elucidated detailed molecular- and biophysical mechanisms of membrane transporters. However, much less has been published about how cells effectively maneuver the complex 3D environments of living tissues. A research team from the University of Southern Denmark, led by Professor Carsten Uhd Nielsen, aims to study the function of membrane transporters. They will be using Ossiform®’s P3D Scaffolds as an appropriate platform. With this technology, the group aspires to simulate a dynamic in vivo-like environment to facilitate pharmaceutical applications of membrane transporter.